Mercedes Sprinter Engine Oil Cooler – OEM | OM642 3.0L V6 | #6421800165 (2010–2021)

DESCRIPTION:

The engine oil cooler on the OM642 3.0L V6 is one of the most well-documented failure points on the entire Sprinter platform. When the cooler or its seals fail, engine oil and coolant mix — and the consequences range from costly to catastrophic. This OEM replacement oil cooler restores proper oil temperature regulation and eliminates the risk of cross-contamination before it reaches your engine.

What This Part Does

The engine oil cooler uses engine coolant to regulate oil temperature, keeping oil viscosity stable under heavy loads and preventing overheating in the lubrication circuit. It mounts directly to the engine block and is part of the same assembly that houses the oil filter. When the internal seals degrade — a common occurrence on high-mileage OM642 engines — coolant enters the oil circuit or vice versa, leading to milky oil, coolant loss, and potential engine damage.

Common Signs of Oil Cooler Failure

• Milky or foamy oil on the dipstick or oil cap
• Unexplained coolant loss with no visible external leak
• White residue in the coolant reservoir
• Oil contamination in the coolant system

When to Replace It

Replace the oil cooler at the first sign of coolant-oil cross-contamination, or proactively on high-mileage OM642 engines as a preventive measure. Always replace the oil cooler seals at the same time — and thoroughly flush both the oil and coolant circuits before returning the engine to service.

Fitment

• 2010–2021 Mercedes-Benz Sprinter 2500 – 3.0L V6 Diesel (OM642)
• 2010–2021 Mercedes-Benz Sprinter 3500 – 3.0L V6 Diesel (OM642)
• 2019–2020 Mercedes-Benz Sprinter 3500XD – 3.0L V6 Diesel (OM642)
• 2007–2009 Dodge/Freightliner Sprinter 2500/3500 – 3.0L V6 Diesel (OM642)

Always verify your VIN before ordering. Contact us and we'll confirm fitment before you buy.

Part Numbers

• Mercedes OEM: 6421800165 / A6421800165 / 642-180-01-65
• SKU: 6421800165H