Mercedes Sprinter Throttle Body Housing Gasket – Genuine OEM | OM642 3.0L V6 | #6421410180

DESCRIPTION:

Any time the throttle body comes off the OM642 intake flange, this gasket must be replaced. It's a one-time-use seal between the throttle body housing and the intake manifold flange — and reusing the original risks an intake air leak that disrupts the air-fuel ratio, triggers fault codes, and causes rough running. This Genuine Mercedes-Benz throttle housing gasket is the correct OEM replacement and one of the most cost-effective seals on the engine.

What This Part Does

The throttle body housing gasket seals the mating surface between the electronic throttle body (regulating flap) and the plastic intake flange on the OM642 engine. Even a small leak at this junction introduces unmetered air into the intake manifold downstream of the MAF sensor — causing lean running conditions, rough idle, and fault codes that can be difficult to diagnose without inspecting the sealing surfaces directly.

When You'll Need This

• Throttle body removal or replacement (part #6420900270)
• Intake manifold service requiring throttle body removal
• Any service where the throttle body flange is unbolted
• Diagnosing idle or air-fuel trim issues after intake service

Note: Always replace with a new gasket — never reuse the original once compressed. This is a low-cost consumable that should be standard procedure any time the throttle body is removed.

Fitment

• 2010–2022 Mercedes-Benz Sprinter 2500 – 3.0L V6 Diesel (OM642)
• 2010–2022 Mercedes-Benz Sprinter 3500 – 3.0L V6 Diesel (OM642)
• 2018–2022 Mercedes-Benz Sprinter 3500XD – 3.0L V6 Diesel (OM642)
• 2007–2009 Dodge/Freightliner Sprinter 2500/3500 – 3.0L V6 Diesel (OM642)

Always verify your VIN before ordering. Contact us and we'll confirm fitment before you buy.

Part Numbers

• Mercedes OEM: 6421410180 / A6421410180 / 642-141-01-80
• SKU: 6421410180OE
• Related: Throttle Body #6420900270, Intake Manifold Gasket #6421410580